Fatty Acid Synthesis and PPARα Hand in Hand

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چکیده

منابع مشابه

Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose

While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. Liver fatty acid binding protein (L-FABP), a mediator of long chain fatty acid signaling to peroxisome proliferator-activated receptor- α (PPAR α ) in the nucle...

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ژورنال

عنوان ژورنال: Chemistry & Biology

سال: 2009

ISSN: 1074-5521

DOI: 10.1016/j.chembiol.2009.08.004